Article Subject
Science
Abstract

In present study the organophosphate was administered at the rate of 15mg/kg of body weight to Swiss albino mice for 45 days to observe the effect on liver of mice. After that, the mice were administered with Azollafiliculoides at the rate of 10 mg/kg of body weight for 30 days. The liver function test (LFT) and lipid peroxidation was evaluated after Profenofos exposure and then Azolla treated groups. The study reveals that Profenofos causes deleterious effect on biochemical parameters as increased in its levels was observed. But, after Azolla administration for 30 days there was significant normalization in the levels of LFT and lipid peroxidation denotes the hepatoprotective and antioxidant activity of Azollafiliculoides

Keywords
Profenofos
organophosphate
Hepatotoxicity
azolla
antidote.
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