Plasmaelectrolytes and blood gases in patients with chronic obstructive pulmonary disease.

Authors

  • Iram Shabir
  • Malik Shahidan Zainab
  • Rabia Farooq
  • Shabhat Rasool
  • Muneeb U Rehman
  • Sabhiya Majid

Keywords:

COPD; hypoxia; electrolyte imbalance; blood gases.

Abstract

Background: COPD is a chronic inflammatory lung disease that causes obstructed airflow from the lungs.Water retention and hypernatremia aretypically observed in the final stages of COPD owing to difficulties of renin- angiotensin axes.

Methods: The present study was conducted to evaluate serum electrolyte levels and blood gases in COPD cases. COPD patients who attended our hospital with acute exacerbations were enrolled in the present study. Plasma electrolyte levels (Sodium and Potassium) and blood gases along with pH were measured.

Results: Two hundred and fifty one cases of COPD and 50 Controls were enrolled in a period of 3 months. Out of these 136 were males (54%) and 115 were females (46%). In control group 22 were males (44%) and 28 were females (56%). The mean age of presentation of COPD patients 62 ± 11.5 yrs (35 to 78yrs) and that of controls was 60±10.8 yrs (32 to 65yrs). Mean plasma sodium and potassium levels in COPD patients were 142.26±10.95mmol/L and 3.81±1.14 mmol/L respectively. Whereas, the levels in the control group were 140±3.79 mmol/L and 3.57±0.48 mmol/L, respectively.

Conclusion: The results from our study support the hypothesis that chronic hypoxia in COPD patients was associated with deranged PaCO2 and PaCO2, salt and water retention which activates renin-angiotensin system.

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Published

31-12-2018

How to Cite

Shabir, I., Zainab, M. S., Farooq, R., Rasool, S., U Rehman, M., & Majid, S. (2018). Plasmaelectrolytes and blood gases in patients with chronic obstructive pulmonary disease. Caribbean Journal of Sciences and Technology, 6(1), 76–79. Retrieved from https://caribjscitech.com/index.php/cjst/article/view/22

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Section

Research Article

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