Caribbean Journal of Sciences and Technology https://caribjscitech.com/index.php/cjst <p style="text-align: justify;"><em>Caribbean Journal of Science and Technology (CJST)</em> is a half yearly (from 2022), international, open access, peer-reviewed Journal and committed to publish multidisciplinary subjects related to biological, chemical, pharmaceutical, and all technological sciences. Further, CJST preferably encourages articles with novelty. CJST publishes manuscripts of the type Full-length research articles, Review articles, Mini-reviews, Short communications, Case Studies, Perspectives and Letters to the Editor.</p> en-US editors@caribjscitech.com (M/s. ChemBio International) support@ubitechsolutions.com (Ubitech Solutions Pvt Ltd) Fri, 19 Jan 2024 09:18:30 +0000 OJS 3.3.0.8 http://blogs.law.harvard.edu/tech/rss 60 Solvent-free Synthesis of Fused Pyrimidone Derivatives from Baylis-Hillman Acetates https://caribjscitech.com/index.php/cjst/article/view/299 <p>By using the Baylis-Hillman acetates as the starting materials, an improved eco-friendly process for the synthesis of fused pyrimidone derivatives has been established. These reactions provide considerable yields (67-78%) of fused pyrimidone derivatives and are easily carried out under mild, solvent-free conditions.</p> Srihari Ch, Siva Rama Krishna Reddy V, Santha Kumari Merugu, Valli Purnima Bollikolla, Siddique Akber Ansari, Ravi Varala, Hari Babu Bollikolla Copyright (c) 2023 Caribbean Journal of Sciences and Technology https://caribjscitech.com/index.php/cjst/article/view/299 Sun, 31 Dec 2023 00:00:00 +0000 An investigation on the effects of nanoplastic particles on Chlorella vulgaris enzymes and its function on removal of nitrate and phosphate https://caribjscitech.com/index.php/cjst/article/view/307 <p>Plastic waste at sea has been a primary environmental concern for years. The degradation of plastics into small pieces leads to the formation of nanoplastics (NPs) (less than 100 nm) that can enter the environment. Polystyrene is one of the most common plastics, a product of the polymerization of styrene monomers. In this study, the toxic effects of amino polystyrene (PS-NH<sub>2</sub>) NPs with sizes 90 (PS-NH<sub>2</sub>-90), 200 (PS-NH<sub>2</sub>-200), and 300 (PS-NH<sub>2</sub>-300) nm with four different concentrations after 72 hours on viability, activity of enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione S-Transferase (GST) and reduced glutathione (GSH), carbonyl protein and sulfhydryl protein and antioxidant activity assay by DPPH reagent on the <em>Chlorella vulgaris</em> were investigated. In all enzymatic assays, except the glutathione (GSH) and sulfhydryl protein, the size of 90 nm showed lowest value. Intriguingly, flow cytometry assessment showed a substantial reduction in the viability at PS-NH<sub>2</sub>-90 treated samples for 72 h which means that as the size of the nanoplastic decreases, its toxicity will increase. The toxicity effect of 90 nm NPs with a concentration of 200 mg/L on the microalgae <em>C. vulgaris</em> (with a concentration of 25000 Cells/mL) with the aim of bioremediation of nitrate (with a concentration of 50 mg/L) and phosphate (with a concentration of 6 mg/L) were investigated. According to the obtained results, NPs with a concentration of 200 mg/L with a size of 90 nm have the highest toxicity on the nitrate and phosphate bioremediation by the <em>C vulgaris</em> with a concentration of 25000 Cells/mL.</p> Parichehr Hanachi, Maryamsadat Shahidi, Mehdi Khoshnamvand, Masoomeh Shafiei, Hamieh Goshtasbi Copyright (c) 2023 Caribbean Journal of Sciences and Technology https://caribjscitech.com/index.php/cjst/article/view/307 Sun, 31 Dec 2023 00:00:00 +0000 Enhancing Administrative Efficiency with HIT in Federal Healthcare https://caribjscitech.com/index.php/cjst/article/view/309 <p>The federal healthcare system in the United States serves millions of Americans, and ensuring the highest quality of care is paramount. Health information technology (HIT) presents a powerful tool to achieve this goal. This paper explores the potential of HIT in improving quality across various aspects of federal healthcare, including clinical care, patient engagement, population health, and administrative efficiency. It examines specific functionalities such as electronic health records (EHRs), telehealth, clinical decision support systems (CDSS), and data analytics. Challenges and barriers hindering optimal HIT utilization are discussed, along with solutions and best practices for successful implementation. By leveraging HIT effectively, the federal healthcare system can enhance quality, optimize resource allocation, and empower patients in their own health journey.</p> <p>This research concludes that by embracing HIT advancements, investing in infrastructure, and training, and prioritizing data-driven initiatives, the federal healthcare system can embark on a transformative journey towards enhanced quality, improved access.</p> Sripriya Bayyapu Copyright (c) 2024 Caribbean Journal of Sciences and Technology https://caribjscitech.com/index.php/cjst/article/view/309 Sun, 31 Dec 2023 00:00:00 +0000