HEPATOPROTECTIVE AND ANTIOXIDANT EFFECT OF AZOLLA FILICULOIDES ON PROFENOFOS INDUCED HEPATOTOXICITY IN SWISS ALBINO MICE

Abstract

In present study the organophosphate was administered at the rate of 15mg/kg of body weight to Swiss albino mice for 45 days to observe the effect on liver of mice. After that, the mice were administered with Azolla filiculoides at the rate of 10 mg/kg of body weight for 30 days. The liver function test (LFT) and lipid peroxidation was evaluated after Profenofos exposure and then Azolla treated groups. The study reveals that Profenofos causes deleterious effect on biochemical parameters as increased in its levels was observed. But, after Azolla administration for 30 days there was significant normalization in the levels of LFT and lipid peroxidation denotes the hepato protective and antioxidant activity of Azolla filiculoides.