REVIEW ON POSSIBILITIES OF PATOLADI GAN KASHAYAM AS AN ADJUVANT THERAPY TO COMBAT ADVERSE EFFECTS OF CHEMOTHERAPY/RADIOTHERAPY & CANCER

Abstract

Cancer is a mass of tissue formed as a result of abnormal, excessive, uncoordinated, autonomous & purposeless proliferation of cells even after cessation of stimulus for growth which caused it. Chemotherapy, Radiotherapy or the cancer itself may cause changes in the body chemistry that results in anorexia, loss of appetite, pain, hepatotoxicity, mucositis, phlebitis, alopecia, skin rashes, burning sensation & very common nausea, vomiting & immunosuppressant. World Health Organization, Lyon/Geneva 12 Dec.2013 declared, global burden rises to 14.1 million new cases & 8.2 million cancer deaths in 2012. In India, 8,00,000 new cancer patients get registered with the National Cancer Registry Programme in 2013, cancer related deaths found in India 5,56,400 in the year 2010. In Ayurvedic classics, like Charaka Samhita & Sushruta Samhita etc. described cancer as inflammatory or non-inflammatory swelling & mention them as either Granthi (minor neoplasm) or Arbuda (major neoplasm). A lot of research papers have been published related with many ayurvedic herbs and the group of herbs showed significant results in this field. Therefore, this review article has been planned to know possibilities to minimize nausea, vomiting etc. with Patoladi Gan Kashayam; And with the help of this article other herbs can also be in light for research area. All the literatures related to Arbuda which find place in classics explored including the texts like Charaka Samhita, Sushruta Samhita, Vagbhatta Samhita and the Laghutrayi. At the same time the Modern literature including recent advances in the field were also be reviewed.