Synthetic methodologies of anticancer active pyrimidines: Update from 2015-till date

10.55434/CBI.2023.10101

Authors

  • Hari Babu Bollikolla Department of Chemistry, Acharya Nagarjuna University, AP-India https://orcid.org/0000-0003-1308-391X
  • Dhayanidhi s Department of Chemistry, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India
  • Lakshmi Prasanna Yangalasetty Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India
  • Surendranatha Reddy Onteddu Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India
  • Srinivasa Rao Angothu Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India
  • Basavaiah Chandu Department of Nanotechnology, UCS, Acharya Nagarjuna University, Guntur, AP-India
  • VSND Lakshmi G Department of Chemistry, VVR Govt Jr College, Mylavaram-521230, NTR Dist., AP-India
  • Ravi Varala

DOI:

https://doi.org/10.55434/CBI.2023.10101

Keywords:

Pyrimidines, Pharmacological activity, Synthesis, Anti-tumor

Abstract

Pyrimidine and its analogues possess a significant role in medicinal chemistry due to exhibiting pharmacological relevance. Cancer is among the most costly and deadly healthcare burdens globally, and investigation on synthesis of new anticancer agents is an important subject of the current research all over the world. In this mini-review, the authors updated the research literature pertaining to the synthetic methodologies of various pyrimidine derivatives exhibiting anticancer activity. The mini-review is a collection of significant contributions done during Mid 2015-December 2022.

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Author Biographies

Hari Babu Bollikolla, Department of Chemistry, Acharya Nagarjuna University, AP-India

Professor

Department of Chemistry, Acharya Nagarjuna University, AP-India

Dhayanidhi s, Department of Chemistry, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India

Department of Chemistry, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India

Lakshmi Prasanna Yangalasetty, Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India

Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India

Surendranatha Reddy Onteddu, Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India

Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India

Srinivasa Rao Angothu, Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India

Department of Chemistry, Acharya Nagarjuna University, Guntur, AP-India

Basavaiah Chandu, Department of Nanotechnology, UCS, Acharya Nagarjuna University, Guntur, AP-India

Department of Nanotechnology, UCS, Acharya Nagarjuna University, Guntur, AP-India

VSND Lakshmi G, Department of Chemistry, VVR Govt Jr College, Mylavaram-521230, NTR Dist., AP-India

Department of Chemistry, VVR Govt Jr College, Mylavaram-521230, NTR Dist., AP-India

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Published

08-03-2023

How to Cite

Bollikolla, H. B., s, D., Yangalasetty, L. P., Onteddu, S. R., Angothu, S. R., Chandu, B., G, V. L., & Varala, R. . (2023). Synthetic methodologies of anticancer active pyrimidines: Update from 2015-till date: 10.55434/CBI.2023.10101. Caribbean Journal of Sciences and Technology, 11(1), 01–07. https://doi.org/10.55434/CBI.2023.10101

Issue

Vol. 11 No. 1 (2023)

Section

Review Article
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Europe PMC

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